Altium Designer, This software solution is designed to be a complete package. From a design concept to completion it can all be done within a single environment. Some of the features include board and FPGA level design. Embedded systems development. PCB layout and editing

The Cadence® PCB design solution offers the widest range of fully scalable PCB design technologies, which are ideal for everything from the simplest of boards to the most complex, high-speed designs. Included features are; System interconnect modeling, Design capture for large-scale designs, High-speed PCB design, Team-based PCB design, Mainstream PCB design, and Regulatory compliance.

DipTrace, was designed to be a powerful, professional, and easy to use PCB design software sold at a fair price. Options include the following: Layout tool, Schematic capture with export to PCB or Spice, A Pattern editor to create component footprints, and a Component editor to draw your parts. They have a Free Trial software to play with before you buy.
 I love trial software, to get a real feel before you buy...

Eagle by CadSoft Online, if you are looking for an easy to use, powerful and affordable schematic capture and printed circuit board design package that gets the job done. Then this might be the one.
Eagle software has a user friendly interface that is both powerful and affordable. Created for PCB designers an includes Schematic Capture, Board Layout, and Autorouter. (Check out the free ware version to see if this will work for you.)